An Affordable and Eco-friendly Method for Pseudo-five-component Synthesis of Tetrahydropyridines Using Gum Arabic-OPO۳H۲ as a Natural-based Catalyst

An Affordable and Eco-friendly Method for Pseudo-five-component Synthesis of Tetrahydropyridines Using Gum Arabic-OPO3H2 as a Natural-based Catalyst abstract

This study describes a facile and environmentally friendly protocol for the synthesis of highly functionalized tetrahydropyridines via pseudo-five-component reaction of aromatic aldehydes, various amines and ethyl acetoacetate using GA-OPO3H2 as a metal free and natural-based catalyst. In addition to the easy preparation of GA-OPO3H2 from bio-renewable materials, this catalyst can also be recycled and reused without obvious loss of catalytic activity. The synthesis of tetrahydropyridines via this new green methodology offers significant advantages in terms of no use of a solvent, no hazardous waste, uncomplicated work-up and high yields of products.

An Affordable and Eco-friendly Method for Pseudo-five-component Synthesis of Tetrahydropyridines Using Gum Arabic-OPO3H2 as a Natural-based Catalyst Keywords:

Gum Arabic-OPO3H2 , Natural-based catalyst , Tetrahydropyridine , Pseudo-five-component reaction , Solvent-free condition

An Affordable and Eco-friendly Method for Pseudo-five-component Synthesis of Tetrahydropyridines Using Gum Arabic-OPO3H2 as a Natural-based Catalyst authors

Bi Bi Fatemeh Mirjalili

Chemistry Department, Yazd University

Sahar Sadat Hoseinikhah

Chemistry Department, Yazd University

Naeimeh Salehi

Chemistry Department, Yazd University

Abdolhamid Bamoniri

Departent of Organic Chemistry, Faculty of Chemistry, University of Kashan

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https://civilica.com/doc/1766079

Document National Code:

JR_ORGC-7-2_012

Index date: 25 September 2023

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Mirjalili, Bi Bi Fatemeh and Hoseinikhah, Sahar Sadat and Salehi, Naeimeh and Bamoniri, Abdolhamid,1400,An Affordable and Eco-friendly Method for Pseudo-five-component Synthesis of Tetrahydropyridines Using Gum Arabic-OPO3H2 as a Natural-based Catalyst,https://civilica.com/doc/1766079

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Type of center: دانشگاه دولتی

Paper count: 19,876

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