Bis (۱(۳-trimethoxysilylpropyl)-۳-methyl-imidazolium) Nickel Tetrachloride Tethered to Colloidal Silica Nanoparticles as a Superior Catalyst for the Bis-thiazolidinones Preparation

An easy and rapid method for the synthesis of bis-thiazolidinones has been presented by one-pot pseudo-five-component reaction of benzaldehydes, ethylenediamine, ۲-mercaptoacetic acid with bis (۱(۳-trimethoxysilylpropyl)-۳-methyl-imidazolium) nickel tetrachloride tethered to colloidal silica nanoparticles. Atom economy, low catalyst loading, reusable catalyst, applicability to a wide range of substrates and high yields of products are some of the important features of this protocol.

Keywords:

Heterogeneous catalysts , Ionic Liquid , Colloidal silica , Bis-thiazolidinones , One-pot