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Aluminum Oxide Nanoparticle as a Valuable Heterogeneous Nanocatalyst in the Synthesis of 2-Aminothiazole Scaffolds

Publish place: Organic Chemistry Research، Vol: 6، Issue: 1
Publish Year: 1399
Type: Journal paper
Language: English
View: 126

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Link to this Paper:
https://civilica.com/doc/1766142

Document National Code:

JR_ORGC-6-1_001

Index date: 25 September 2023

Aluminum Oxide Nanoparticle as a Valuable Heterogeneous Nanocatalyst in the Synthesis of 2-Aminothiazole Scaffolds abstract

An efficient methodology for the preparation of 2-aminothiazoles is achieved by one-pot reaction of methylcarbonyls, thiourea and iodine in the presence of an aluminum oxide nanoparticle as an active nanocatalyst at 85 °C in DMSO solvent. Al2O3 nanoparticles have been prepared via co-precipitation method and their structures were confirmed using Fourier transform infrared radiation (FT-TR), X-ray diffraction (XRD), scanning electron microscopic (SEM), and energy-dispersive analysis of X-ray (EDAX) analyses. Advantages of this efficient synthetic approach include higher purity and excellent yield of products, easy isolation of products and convenient manipulation.

Aluminum Oxide Nanoparticle as a Valuable Heterogeneous Nanocatalyst in the Synthesis of 2-Aminothiazole Scaffolds Keywords:

1 , 3-Thiazoles , Al2O3 nanoparticles , Methylcarbonyls , One-pot synthesis , Heterogeneous catalyst

Aluminum Oxide Nanoparticle as a Valuable Heterogeneous Nanocatalyst in the Synthesis of 2-Aminothiazole Scaffolds authors

Zahra Shokrani

aLaboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry and Biochemistry, University of Kashan, P.O. Box: ۸۷۳۱۷-۵۱۱۶۷, Kashan, I.R, Iran.

Zohre Zarnegar

Research Affiliate, Department of Chemistry, University of Payame Noor, P.O. BOX ۱۹۳۹۵-۴۶۹۷, Tehran-IRAN

Javad Safari

aLaboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry and Biochemistry, University of Kashan, P.O. Box: ۸۷۳۱۷-۵۱۱۶۷, Kashan, I.R, Iran.