Efficient Oxidative Dehydrogenation of Dihydropyrimidinones and Thiocyanation of Aromatic Compounds Using ۱,۱,۲,۲-Tetrahydroperoxy-۱,۲-diphenylethane as the Oxidant

A new, efficient and mild approach for the oxidative dehydrogenation of dihydropyrimidinones and thiocyanation of aromatic compounds using ۱,۱,۲,۲-tetrahydroperoxy-۱,۲-diphenylethane (THPDPE) as a terminal oxidant was developed. Initially, various substrates bearing different electron-donating and electron-releasing functionalities were synthesized and next under the optimized reaction conditions the desired products were yielded after an easy work-up and the structures were characterized compared with those reported. All of the reactions proceeded in short reaction times and ۱,۱,۲,۲-tetrahydroperoxy-۱,۲-diphenylethane (THPDPE) proved its potential to yield the desired products in high yields.

Keywords:

Dehydropirimidinones , Oxidative dehydrogenation , Thiocyanation , ۱ , ۲ , ۲-Tetrahydroperoxy-۱ , ۲-diphenylethane , Pyrimidinones