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Mild and Solvent-free Synthesis and Antibacterial Evaluation of Novel Sulfonamides Containing Hydroxyl Groups

Publish place: Organic Chemistry Research، Vol: 5، Issue: 1
Publish Year: 1398
Type: Journal paper
Language: English
View: 127

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Link to this Paper:
https://civilica.com/doc/1766212

Document National Code:

JR_ORGC-5-1_003

Index date: 25 September 2023

Mild and Solvent-free Synthesis and Antibacterial Evaluation of Novel Sulfonamides Containing Hydroxyl Groups abstract

A series of interesting sulfonamides containing hydroxyl group were synthesized under solvent-free conditions. The synthetic route involves the selective reaction of amino alcohol and sulfonating agents. The sulfonamides were obtained by simple procedure after an easy work-up in high yield and purity, and characterized by IR, 1H NMR and 13C NMR analysis. These compounds were tested for antibacterial activity against four bacterium including Escherichia Coli, Staphylococcus Aurous, Bacillus Subtilis and Salemonella Typhi.

Mild and Solvent-free Synthesis and Antibacterial Evaluation of Novel Sulfonamides Containing Hydroxyl Groups Keywords:

Sulfonamide , Solvent-free , antibacterial , Amino alcohol

Mild and Solvent-free Synthesis and Antibacterial Evaluation of Novel Sulfonamides Containing Hydroxyl Groups authors

Ahmad Reza Massah

Departrment of Chemistry, Shahreza Branch, Islamic Azad University

Seyedeh Simin Dakhilpour

Department of Chemistry,Shahreza Branch, Islamic azad University,

Sara Ebrahimi

Department of Chemistry, Shahreza Branch, Islamic Azad University

Saeed Naseri

Department of Chemistry, Shahreza Branch, Islamic Azad University

Mina Nateghi

Department of Chemistry, Shahreza Branch, Islamic Azad University