Mild and Solvent-free Synthesis and Antibacterial Evaluation of Novel Sulfonamides Containing Hydroxyl Groups

A series of interesting sulfonamides containing hydroxyl group were synthesized under solvent-free conditions. The synthetic route involves the selective reaction of amino alcohol and sulfonating agents. The sulfonamides were obtained by simple procedure after an easy work-up in high yield and purity, and characterized by IR, ۱H NMR and ۱۳C NMR analysis. These compounds were tested for antibacterial activity against four bacterium including Escherichia Coli, Staphylococcus Aurous, Bacillus Subtilis and Salemonella Typhi.

Keywords:

Sulfonamide , Solvent-free , antibacterial , Amino alcohol

Authors

Ahmad Reza Massah

Departrment of Chemistry, Shahreza Branch, Islamic Azad University

Seyedeh Simin Dakhilpour

Department of Chemistry,Shahreza Branch, Islamic azad University,

Sara Ebrahimi

Department of Chemistry, Shahreza Branch, Islamic Azad University

Saeed Naseri

Department of Chemistry, Shahreza Branch, Islamic Azad University

Mina Nateghi

Department of Chemistry, Shahreza Branch, Islamic Azad University

Certificate
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https://civilica.com/doc/1766212

شناسه ملی سند علمی:

JR_ORGC-5-1_003

تاریخ نمایه سازی: 3 مهر 1402

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Massah, Ahmad Reza and Dakhilpour, Seyedeh Simin and Ebrahimi, Sara and Naseri, Saeed and Nateghi, Mina,1398,Mild and Solvent-free Synthesis and Antibacterial Evaluation of Novel Sulfonamides Containing Hydroxyl Groups,https://civilica.com/doc/1766212

Scientometrics

The specifications of the publisher center of this Paper are as follows:

Ranking of Islamic Azad University of Shareza

Type of center: Azad University

Paper count: 1,771

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