Multicomponent Solvent-Free Synthesis, Antimicrobial and Antifungal Evaluation of Novel N-Amino Benzylthiolates
Publish place: Organic Chemistry Research، Vol: 4، Issue: 2
Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
View: 54
This Paper With 9 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_ORGC-4-2_002
تاریخ نمایه سازی: 3 مهر 1402
Abstract:
Novel N-amino benzylthiolates were synthesized via multicomponent reaction of malononitrile, isothiocyanates and benzyl halides under conventional and solvent-free conditions. Various electron-donating and -withdrawing substitutes within both isothiocyanates and benzyl halides were used to demonstrate the efficiency of new methodology. A broad spectrum of antibacterial and antifungal activities were observed especially within benzyl halides containing electron-withdrawing aryl substituents.
Keywords:
Authors
Hamid Beyzaei
Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran
Hossein Heidari
Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran
Reza Aryan
Department of Chemistry, Faculty of Science, University of Zabol, Zabol, Iran