Biginelli Multicomponent Condensation Reaction Promoted by ۴,۴ʹ-Bipyridinium Dichloride Ordered Mesoporous Silica Nanocomposite under Solvent Free Conditions

In this paper, ۴,۴ʹ-bipyridinium dichloride  supported SBA-۱۵ (SBA@BiPy۲+ ۲Cl-) was used for the synthesis of dihydropyrimidinones. The synthesized catalyst was characterized by FT-IR spectroscopy, scanning electron microscopy (SEM), Transmission electron microscopy (TEM) and Thermogravimetric analysis (TGA). This nanocomposite was shown to be an efficient heterogeneous catalyst for the synthesis of dihydropyrimidinones derivatives via one-pot multicomponent method under solvent-free conditions. In addition, the catalyst can be recycled several times with no significant loss of catalytic activity.

Keywords:

Organic-inorganic hybrid nanocomposite , Dicationic ۴ , ۴ʹ-bipyridine silica hybrid nanocomposite , Mesoporous silica , Dihydropyrimidinones