Haematological assessment of the red tilapia “Oreochromis sp.” exposed to sublethal concentrations of Eryytromycin antibiotics

Erythromycin (ERY) is one of the most common antibiotics used in human and veterinary practices, leading to ubiquitous environmental distribution and possible toxicity to non-target organisms. The purpose of this study was to determine sub-lethal effects of ERY on some heamatological paramaters of the red tilapia (Oreochromis sp) have a total weight (Wt) which varies (۱۹≤Wt (g)≤۸۹) with a length varies (۱۰.۵ ≤Lt(cm)≤۱۶.۴) was investigated using static bioassay system for ۲۸ day. The sub lethal concentrations used were (۰.۳, ۱.۷, ۱۰, ۶۰ and ۳۰۰ µg/L) and ۰.۰۰(control) mg. L-۱. There were not significant differences (p≤۰.۰۵) in th water quality parameters monitored in both test aquariums and the control. The blood-biochemical and lipid balance confirms that individuals with Aq۵ (CL۹۰) have a mediocre blood disorder [hypochromic microcytic anemia; leukocytosis associated with leukopenia] with an immune response defined by thrombocytopenia. Overall, all of the bioassays (Aq۱, Aq۲, Aq۳, Aq۴ and Aq۵) present a pathology of stress and energy depletion.

Keywords:

Oreochromi ssp , Erythromycin , Pathologies , Haematology , Toxicology