سیویلیکا را در شبکه های اجتماعی دنبال نمایید.

Evaluation of Carotid Artery Intima-media Thickness in the Patients With and Without Helicobacter pylori Infection

Publish Year: 1401
Type: Journal paper
Language: English
View: 124

This Paper With 8 Page And PDF Format Ready To Download

Export:

Link to this Paper:

Document National Code:

JR_QJVC-3-3_010

Index date: 4 November 2023

Evaluation of Carotid Artery Intima-media Thickness in the Patients With and Without Helicobacter pylori Infection abstract

Background and Aim: Bacterial infections can stimulate immune responses, directly or indirectly, mainly by interacting with inflammatory and immune pathways, which negatively affect cardiovascular risk factors. The severity of Helicobacter pylori infection can be an essential determinant of its atherogenic potential. Carotid intima-media thickness (CIMT) is a quantitative ultrasound-based parameter that may predict a subclinical atherosclerotic disease in an individual. Considering the previous studies and lack of accurate known etiology for atherosclerosis and the high prevalence of this infection in growing communities, particularly in Iran, this study was conducted to investigate the relationship between H. pylori infection and CIMT. We compared IMT in infected and non-infected patients with H. pylori in the present study. Materials and Methods: This descriptive study was performed on 68 patients undergoing endoscopy in the gastrointestinal ward of Ali Ibn Abi Talib Hospital in Rafsanjan City, Iran, from 2020 to 2021. The sampling method was convenience sampling. After selecting eligible patients, a biopsy specimen was taken from the antrum and gastric mucosa during endoscopy. Based on the rapid urease test results, patients were divided into two equal groups (n=34) infected and non-infected with H. pylori. Patients’ demographic information and serum C-reactive protein (CPR) level were extracted from the patients’ files and entered into a pre-designed checklist. Then, the CIMT was measured by a radiologist using a GE Voluson E6 color Doppler ultrasound machine. Data were collected and analyzed in SPSS software, version 22. A significance level of 5% was considered. Results: In infected and non-infected patients with H. pylori, no significant difference was observed between the mean age (P=0.215), body mass index (P=0.074), gender (P=1), smoking (P=0.779) and family history (P=0.801). However, the mean level of CPR (P=0.007) and CIMT (P=0.023) in patients infected with H. pylori were significantly different from those not infected with H. pylori and patients infected with H. pylori showed significantly higher values of CRP and CIMT. Conclusion: The results of this study showed that patients infected with H. pylori are more prone to increased CIMT than non-infected individuals with H. pylori, which may be associated with increased CRP as an inflammatory marker in the inflammatory pathway.

Evaluation of Carotid Artery Intima-media Thickness in the Patients With and Without Helicobacter pylori Infection Keywords:

Evaluation of Carotid Artery Intima-media Thickness in the Patients With and Without Helicobacter pylori Infection authors

Zahra Eslamian

Radiology Specialist, Department of Radiology, School of Medicine, Ali-Ibn Abi-Talib Educational and Tretment Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran

Farahmand

Radiology Specialist, Department of Radiology, School of Medicine, Ali-Ibn Abi-Talib Educational and Tretment Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran

Sajjad Rezvan

Radiology, Qom University of Medical Sciences, Qom, Iran.

Afshin Tahmasbi

Department of Internal Medicine, School of Medicine, Ali-Ibn Abi-Talib Educational and Treatment Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Zahra Kamyab

Clinical Research Development Unit, School of Medicine, Ali-Ibn Abi-Talib Educational and Treatment Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Mohammad-Hossein Mokhtarian

Department of Clinical Sciences, Faculty of Veterinary Medicine, Garmsar Branch, Islamic Azad University, Garmsar, Iran.

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
Roth GA, Johnson C, Abajobir A, Abd-Allah F, Abera SF, ...
Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE. ...
Feng Y, Zhou W, Luo L, Xu W. Helicobacter pylori ...
نمایش کامل مراجع