Prevalence of Oral and Craniofacial Manifestations of Hematological Dyscrasias at Shiraz Nemazee Hospital
Publish place: Middle East Journal of Cancer، Vol: 5، Issue: 3
Publish Year: 1393
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_MISJ-5-3_005
تاریخ نمایه سازی: 25 آبان 1402
Abstract:
Background: Hematological disorders may present with a number of non-specific orofacial manifestations that must be diagnosed and referred to specialists for treatment. Since the orofacial manifestations can be the first clinical presentation which indicates the presence of an underlying disease, it is important for dentists to be aware of these manifestations. The present study aims to evaluate the orofacial presentations of some hematological diseases in order to familiarize dentists with these manifestations.Methods: This descriptive cross-sectional study evaluated the oral conditions of patients recently hospitalized with histories of blood dyscrasia and bone marrow transplantation in Shiraz Nemazee Hospital during ۲۰۱۰-۲۰۱۱. From ۵۰ patients, there were ۳۳ (۶۶%) males and ۱۷ (۳۴%) females. The age of participants ranged from ۱۲-۷۷ years of age.Results: Examined patients had the following manifestations: head and neck region lymphadenopathy (۴۲%), hairy tongue, atrophy of the oral mucosa, ulcers, red and white lesions, Candida albicans infection and gingival lesions that included spontaneous gingival bleeding, gingival hypertrophy and ecchymosis, in addition to diffuse herpetic infections on the buccal mucosa and bony lesions. The most common blood dyscrasia in the study patients was acute myeloid leukemia (AML) (۴۸%). Our findings determined that lymphadenopathy (۴۲%) was the most common orofacial manifestation of hematological diseases.Conclusion:On occasion, dentists maybe the first medical professional to encounter hematological diseases. Since early detection of these disorders can increase patient survival, it is necessary for dentists to become completely familiar with these oral manifestations.
Authors
Janan Ghapanchi
Department of Oral & Maxillofacial Disease, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
Mostafa Rezaee
Department of Oral & Maxillofacial Disease, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
Fereshteh Kamali
Department of Oral Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
Fatemeh Lavaee
Department of Oral & Maxillofacial Disease, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
Eissa Shakib
School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran