Antibacterial Activity and Chemical Composition of Ajowan (Carum copticum Benth. & Hook) Essential Oil

Publish Year: 1389
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JASTMO-13-2_007

تاریخ نمایه سازی: 1 آذر 1402

Abstract:

Gas chromatography (GC) and gas chromatography mass spectrometry (GC-MS) were employed to determine the chemical composition of essential oil obtained from dry fruits of Carum copticum. Thymol (۳۶.۷%), -terpinene (۳۶.۵%) and -cymene (۲۱.۱%) were found to be the major constituents of the oil. The anti-bacterial activities of the oil were mainly investigated against food poisoning bacteria (Salmonella thyphimorium, Pseudomonas aeruginosa, Entero-pathogenic Escherichia coli, and Staphylococcus aureus) by broth microdilution and agar diffusion methods. The oil exhibited significant anti-bacterial activities against all the examined bacteria. In conclusion, the results of this study showed that the oil of Ajowan is rich in monoterpenes and it may be used as a natural anti-bacterial agent in drug and food industries.

Keywords:

Essential oil , Carum copticum , Anti-bacterial activity , Gas Chromatography Mass Spectrometry

Authors

Gh. R. Goudarzi

Department of Immunology and Bacteriology¸ Medical School¸ Lorestan University of Medical Sciences, Lorestan, Islamic Republic of Iran.

M. J. Saharkhiz

Department of Horticultural Sciences, Collage of Agriculture, Shiraz University, Shiraz, Islamic Republic of Iran.

M. Sattari

Department of Bacteriology¸ School of Medical Sciences¸ Tarbiat Modares University, Tehran, Islamic Republic of Iran

K. Zomorodian

Department of Medical Mycology and Parasitology, School of Medicine, Shiraz University of Medical Sciences, Shiraz , Islamic Republic of Iran.