Antifungal effect of the effect of Securigera securidaca L. vaginal gel on Candida species
Publish place: Current Medical Mycology، Vol: 5، Issue: 3
Publish Year: 1398
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_CUMM-5-3_006
تاریخ نمایه سازی: 11 آذر 1402
Abstract:
Background and Purpose: Candida species are opportunistic fungi, capable of causing acute and chronic infections in the gastrointestinal tract, vagina, and oral mucosa, among which Candida albicans is the most important species. The Securigera securidaca L. is used as an antiseptic to treat some diseases in traditional Iranian medicine. The aim of this study was to evaluate the antimicrobial activity of S. securidaca extracts and vaginal gel against different Candida species. Materials and Methods: Antifungal effects of different extracts and vaginal gel of S. securidaca were investigated against Candida species. By using well diffusion test, different concentrations of the collected S. securidaca extracts and vaginal gel were examined to test their antifungal activity against C. albicans, C. parapsilosis, and C. krusei. Results: The ethanol extract and vaginal gel with the ethanol extract of S. securidaca showed the most anti-fungal activity against all three strains. Conclusion: The S. securidaca extract had a significant inhibitory effect on the different species of Candida; however, the highest inhibitory effect was found against C. albicans. In order to treat candidiasis, more research is required to check the efficacy of this plant in this domain.
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Authors
Atefeh Raesi Vanani
Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Masoud Mahdavinia
Toxicology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Heibatullah Kalantari
Toxicology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Saeed Khoshnood
Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran
Maryam Shirani
Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
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