Associations between Dietary Total Antioxidant Capacity and Sarcopenia in Elderly PeopleAzadeh Aminianfar

Introduction: No study has investigated the relationship between dietary total antioxidant capacity and sarcopenia so far. This study aimed to investigate the association between dietary Total Antioxidant Capacity (d-TAC) and sarcopenia in elderly adults.Materials and Methods: In this cross-sectional study we enrolled ۳۰۰ elderly people (۱۵۰ men and ۱۵۰ women) aged ≥۵۵ years using cluster random sampling method. Sarcopenia was defined based on European Working Group on Sarcopenia (EWGSOP) definition. A DXA scanner, a squeeze bulb dynamometer and a ۴-Meter walk gait speed test was used to measure Appendicular Skeletal Muscle (ASM), muscle strength and muscle performance respectively. We also used a Block-format ۱۱۷-item food frequency questionnaire (FFQ) to assess dietary intakes of participants. Multivariable logistic regression models were applied to examine the association between dTAC and sarcopenia.Results: Mean ± SD age of study participants and their BMI was ۶۶.۸ ±۷.۷۲ year and ۲۷.۳ ± ۴.۲ kg/m۲, respectively. People in the highest tertile of d-TAC had the greatest hand grip strength (۱۱.۹ ± ۳.۶۳ vs. ۱۰.۴ ± ۳.۵۵ psi, p=۰.۰۰۹) and had lower odds of sarcopenia compared with those in the lowest tertile, either before (OR= ۰.۳۹ ،۹۵% CI: ۰.۱۷, ۰.۸۸) or after adjustment for potential confounders (OR= ۰.۳۳ ،۹۵% CI: ۰.۱۱, ۰.۹۵). No other significant association was seen between d-TAC and components of sarcopenia.Conclusion: We found an inverse association between dietary total antioxidant capacity and odds of sarcopenia. No significant association was seen between d-TAC and individual components of sarcopenia. Further studies are needed to confirm our findings.

Keywords:

Sarcopenia , total antioxidant capacity , d-TAC , elderly , cross-sectional.