Chemical Composition of Methanolic Extracts of Scutellaria orientalis L.: Digitoxin and Neocurdione Detection by Gas Chromatography/Mass Spectrometry
Publish place: Pharmaceutical and Biomedical Research، Vol: 8، Issue: 1
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
View: 66
This Paper With 14 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_PBRE-8-1_006
تاریخ نمایه سازی: 10 دی 1402
Abstract:
Background: Scutellaria orientalis subsp. virens is a species of Scutellaria genus (the Lamiaceae family). The aqueous root extract of S. orientalis has been traditionally used by Iranians to treat neurological disorders, dermatitis, and bronchitis. The active compounds in the roots and shoots of S. orientalis are mainly flavones such as baicalin, wogonoside, scutellarin, and their aglycons. These compounds have anticancer, anti-inflammatory, antiviral, and antibacterial activities.
Objectives: This study aimed to identify the root and shoot methanolic extracts components of S. orientalis.
Methods: The Gas Chromatography/Mass Spectrometry (GC/MS) method was used to identify components of S. orientalis.
Results: GC/MS analysis of methanolic root extract identified ۶۳ components, such as flavonoids, fatty acids, ketones, glucosides, amino acids, steroids, and alkaloids, with flavonoids like wogonin (۱۲.۶%) as the main components. S. orientalis methanolic shoot extract analysis also identified ۷۹ components such as ketones, alcohols, sesquiterpenes, fatty acids, steroids, vitamins, and diterpenoids, with digitoxin and neocurdione as the main components. In addition, the Fourier Transform Infrared (FTIR) analysis of roots and shoots confirmed the presence of normal polymeric O-H stretch, aliphatic alkenes, aromatic alkenes, amides, ammonium ions, alcohols, ethers, carboxylic acids, esters, amines, and alkanes in the structure of identified compounds by GC/MS analysis.
Conclusion: The obtained results revealed the presence of biologically active compounds that can be used for various herbal formulations.
Keywords:
Authors
Zahra Gharari
Department of Plant Production and Genetics, Faculty of Agriculture, University of Zanjan, Zanjan, Iran.
Khadijeh Bagheri
Department of Plant Production and Genetics, Faculty of Agriculture, University of Zanjan, Zanjan, Iran.
Ali Sharafi
Zanjan Pharmaceutical Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :