The Effect of Pre-exposure to Radiofrequency Radiations Emitted from a GSM Mobile Phone on the Suseptibility of BALB/c Mice to Escherichia coli

Publish Year: 1391
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JBPE-2-4_003

تاریخ نمایه سازی: 3 بهمن 1402

Abstract:

Background: Pre-exposure to radiofrequency radiations of mobile phones would significantly increase the survival rate of exposed animals compared to those exposed to a lethal dose of gamma radiation alone. Stimulation of the immune system is believed to be a key mechanism for the induction of this phenomenon, the so-called “adaptive response.” The immune system protects organisms against infection with multiple lines of defense of increasing specificity.Objective: In this animal study, the effect of pre-exposure to radiofrequency on the survival adaptive response of a group of BALB/c mice which received intraperitoneal injections of Escherichia coli was investigated.Methods: Groups of BALB/c mice (exposure groups) were exposed to radiofrequency radiations emitted from a GSM mobile phone for ۲, ۴, ۸ or ۱۲ hours a day for ۳ days. Other groups (sham exposed groups) were treated as exposure groups but the mobile phone was switched off during the experiment. On day ۴, animals received intraperitoneal injections of E. coli. Survival of the animals was carefully monitored by an expert scientist.Results: ۱۵ days after exposure to the bacteria, the survival rate of the animals exposed to mobile radiations for ۱۲ h/day was significantly (p=۰.۰۲۱) higher than those which only exposed to the bacteria (no pre-exposure to radiofrequency).Conclusion: Pre-exposure of BALB/c mice to radiofrequency radiations emitted from a GSM mobile phone increases their resistance to E. coli infection. This finding may have important clinical implications in treating bacterial infections.

Authors

S. M. J. Mortazavi

Professor of Medical Physics, Medical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

M. Motamedifar

Associate Professor of Microbiology, Department of Bacteriology, School of Medicine and Shiraz HIV/AIDS Research Center (SHARC), Shiraz University of Medical Sciences, Shiraz, Iran

A. R. Mehdizadeh

Assistant Professor of Medical Physics, Medical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

G. Namdari

Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

M. Taheri

Lecturer of Microbiology, Laboratory Sciences Department, School of Allied Medical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran