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Propolis and its therapeutic effects on renal diseases, a review

Publish place: Iranian Journal of Basic Medical Sciences، Vol: 27، Issue: 4
Publish Year: 1403
نوع سند: مقاله ژورنالی
زبان: English
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لینک ثابت به این Paper:
https://civilica.com/doc/1901167

شناسه ملی سند علمی:

JR_IJBMS-27-4_001

تاریخ نمایه سازی: 14 بهمن 1402

Abstract:

Propolis is produced by bees using a mixture of bees wax and saliva. It contains several bioactive compounds that mainly induce anti-oxidant and anti-inflammatory effects. In this review, we aimed to investigate the effects of propolis on kidney diseases. We used “Kidney”, “Disease”, “Propolis”, “Renal”, “Constituent”, “Mechanism”, “Infection”, and other related keywords as the main keywords to search for works published before July ۲۰۲۳ in Google scholar, Scopus, and Pubmed databases. The search terms were selected according to Medical Subject Headings (MeSH). This review showed that propolis affects renal disorders with inflammatory and oxidative etiology due to its bioactive compounds, mainly flavonoids and polyphenols. There have been few studies on the effects of propolis on kidney diseases; nevertheless, the available studies are integrated in this review. Overall, propolis appears to be effective against several renal diseases through influencing mechanisms such as apoptosis, oxidative balance, and inflammation.

Keywords:

Anti-inflammatory , Anti-Oxidants , Kidney , Propolis , Toxicity

Authors

Fatemeh Salami

Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Reza Mohebbati

Department of Physiology, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran

Sara Hoseinian

Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Samira Shahraki

Department of Physiology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran

Hossein Hosseinzadeh

Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Abolfazl Khajavirad

Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

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