Lipid Lowering Effects of Aqueous Saffron Extract in Diabetic Rats
Publish place: Report of Health Care، Vol: 2، Issue: 3
Publish Year: 1395
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_RHCA-2-3_001
تاریخ نمایه سازی: 24 بهمن 1402
Abstract:
Introduction: Diabetes mellitus is one of the most common non-communicable and chronic diseases. The present study aimed to review the lipid lowering effects of aqueous saffron extract in diabetic rats. Methods: Sixty diabetic rats with fasting blood glucose of over ۳۰۰ mg/dl were selected as sample and divided in two groups of saffron extract and control. Group of saffron extract received ۲۵ mg/kg daily aqueous saffron extract peritoneally for ۴ weeks. Lipid profile was measured by enzymatic method with zist shimi commercial kits provided by yasa teb Company. For statistical analysis of data, Kalmogorov- Smirnov test and paired sample and independent sample t- tests (p≤۰.۰۵) were used. Results: Findings showed that ۴ weeks saffron extract induces significant reduction in LDL, VLDL, TG and Cho of diabetic rats (p=۰.۰۰۱); nevertheless, it has no significant effect on HDL (p=۰.۰۷). Conclusion: It is concluded that ۴ weeks aqueous saffron extract has lipid lowering effect in diabetic rats.
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Authors
Elham Adibfar
Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Seyed Ali Hoseini
Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Omidreza Salehi
Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Fatemeh Farkhaie
Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
Parvin Shah Hosseini
Doctor of Veterinary Medicine
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