Investigating the Frequency of Candida glabrata in Diabetic Women of Tehran with Recurrent and Non-recurrent Vulvovaginal Candidiasis Using PCR-RFLP Assay

Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
View: 75

This Paper With 8 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_JMMI-7-1_008

تاریخ نمایه سازی: 29 بهمن 1402

Abstract:

Introduction: Vulvovaginal Candidiasis (VVC) is one of the most common genital tract infections among women, especially in diabetic patients. The increasing prevalence of recurrent infections caused by drug-resistant non-albicans species necessitates further studies on diabetic patients and the identification of causative agents by reliable molecular techniques. The obtained results can assist in adopting proper treatment procedures and prevention of recurrent vulvovaginitis (RVVC). Methods: In a cross-sectional study, ۱۵۰ vaginal discharge samples were collected from diabetic women suspected of candidiasis referring to health centers in Tehran province. Following the culture of samples on SDA, CHROMagar Candida and PCR-RFLP were used for presumptive and definitive identification of Candida species, respectively. Results: Out of ۱۱۵ positive patients, ۱۰۵ showed infection with one species, and ۱۰ had a mixed infection with two species. The frequency of Candida glabrata isolated from non-mixed and mixed infections in RVVC group was higher than Candida albicans (۲۷.۸% vs. ۹.۶%), which contradicted the results of the VVC group (۶.۱% vs. ۲۴.۳%). In the RVVC group, therefore, the patients were more infected with non-albicans species than C. albicans (۴۷.۸% vs. ۹.۶%), while in the VVC group the non-albicans were of lower frequency (۱۸.۳% vs. ۲۴.۳%). Conclusion: Our findings showed a statistically significant correlation (P<۰.۰۰۱) between the frequency of C. glabrata and the prevalence of RVVC. On the other hand, that blood sugar, duration of diabetes, and antibiotics usage had significant correlations (P<۰.۰۰۱) with the recurrence of severe symptoms.

Authors

Mansoureh Paknejadi

Department of Pathobiology, Science and Research Branch, Islamic Azad University, Tehran, Iran

Mansour Bayat

Department of Pathobiology, Science and Research Branch, Islamic Azad University, Tehran, Iran

Vadood Razavilar

Department of Pathobiology, Science and Research Branch, Islamic Azad University, Tehran, Iran

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
  • Gandhi TN, Patel MG, Jain MR. Prospective study of vaginal ...
  • LemaVM. Recurrent Vulvo-Vaginal Candidiasis: Diagnostic and Management Challenges in a ...
  • Kalia N, Singh J, Sharma S, Kamboj SS, Arora H, ...
  • Workowski KA, Bolan GA. Sexually transmitted diseases treatment guidelines. Morb ...
  • Diba K, Namaki A, Ayatolahi H, Hanifian H. Comparison of ...
  • Marschalek J, Farr A, Kiss H, Hagmann M, Göbl CS, ...
  • Mintz JD, Martenz MG. Prevalence of Non-albicans Candida Infections in ...
  • Arfiputri D.S, Hidayati A.N, Handayani S, Ervianti E. Risk Factors ...
  • BlosteinF, Levin-Sparenberg E, Wagner J, Foxman B. Recurrent vulvovaginal candidiasis. ...
  • Wang FJ, Zhang D, Liu ZhH, Wu WX, Bai HH, ...
  • Elfeky DS, Gohar NM, EL-Seidi EA, Ezzat MM, AboElew SH. ...
  • Hedayati MT, Taheri Z, Galinimoghadam T, Aghili SR, Yazdani JG, ...
  • Jimoh O, Hannah I, Yakubu SE, Ankuma SJ, Olayinka AT. ...
  • Bonifaz A, Armas-Vázquez A, Tirado-Sánchez A. Fungal Infections in Diabetics. ...
  • Adebiyi OE, Oluwadun A, Daniel OJ, Oritogun RS, Fasanmade AA. ...
  • Bassyouni RH, Wegdan AA, Abdelmoneim A, Said W, AboElnaga F. ...
  • MohammedAB, Ali JH, Abdullah SK. Identification of Candida spp. isolated ...
  • Mahmoudi Rad M, Zafarghandi AS, Amel Zabihi M, Mirdamadi Y, ...
  • Fouladi B, Yadegari M, Rajabibazl M, Fazaeli A, Hashemzadeh MC. ...
  • Mohammadi R, MirhendiH, Yadegari MH,ShadziSh, Jalalizand N. Identification and Frequency ...
  • Korabecna M. The Variability in the Fungal Ribosomal DNA (ITS۱, ...
  • Mirhendi H, Makimura K, Zomorodian K, Meeda N. Differentiation of ...
  • Gunther LSA, Martins HPR, Gimenes F, Abreu ALP, Consolaro MEL, ...
  • Fattouh M, Nasr El-din A, Badawy A, Nour El-din M, ...
  • Kalaiarasan K, Singh R, Chaturvedula L. Fungal Profile of Vulvovaginal ...
  • Shrivastav V.K, Shukla D, Shrivastav A, Jana A.M. Prevalence of ...
  • Sangaré I, Sirima C, Bamba S, Zida A, Cissé M, ...
  • Goulart LS, Santiago EF, Ramon JL, Moura SV, Silva AR, ...
  • Al-mamari A, Al-buryhi M.M, Al-hag S. Species-specific prevalence of vaginal ...
  • Faraji R, Rahimi MA, Rezvanmadani F, Hashemi M. Prevalence of ...
  • Yadav K, Prakash S. Prevalence of Vulvovaginal Candidiasis in Pregnancy. ...
  • Bitew A, Abebaw Y. Vulvovaginal candidiasis: species distribution of Candida ...
  • Wang H, Huang Z, Wu Z, Qi X, Lin D. ...
  • Pondei K, Jeremiah I, Lawani E, Nsikak E. The Prevalence ...
  • Sopian LL, Shahabudin S, Ahmed MA, Lung LTT, Sandai D. ...
  • Alsharifi E.A, Epidemiology of vaginal candidiasis among pregnant women attending ...
  • Habibian R, Jafarzadeh L, Shahriari K. Investigating the relationship between ...
  • Devi LS, Maheshwari M. Speciation of Candida Species Isolated From ...
  • Zhai Y, Liu J, Zhou L, Ji T, Meng L, ...
  • Williams DW, Wilson MJ, Lewis MA, Pots AJ. Identification of ...
  • Mirhendi H, Makimura K, Khoramizadeh MR, Yamaguchi H. A One-Enzyme ...
  • Samiei M, Moaseni M, Ajudanifar H, Karimi N. Molecular identification ...
  • نمایش کامل مراجع