Cost-effectiveness of Methadone Maintenance Treatment Centers in Prevention of Human Immunodeficiency Virus Infection

Background: Acquired immune deficiency syndrome (AIDS) is one of the greatest social health problems in many communities in the twenty-first century. Methadone maintenance treatment (MMT) could decrease HIV infection among injection drug users (IDU). The main aim of this paper was to determine the cost-effectiveness of the governmental MMT program to prevent human immunodeficiency virus (HIV) infection among IDU.Methods: This analytical study was performed through a before-after assessment during a one-year period. Using census sampling, ۲۵۱ IDU referred to the public MMT program of Kerman, Iran, were selected. The expenditures of MMT centers were calculated in the view of government (public sector). The cost-effectiveness was calculated using TreeAge software.Findings: MMT centers averted ۸۶ new cases of HIV infection. The total cost of centers was US۴۷۱ per client in the year. The share of IDU from current expenditures was ۳۵% and from capital expenditures was ۳۲%. Also, methadone per capita for each person who injected drug was US۵۱۴. Per capita expenditure of HIV drug treatment was estimated US۸۵۳۵ per year. Incremental cost effectiveness ratio (ICER) was US۲۸۵۶ per year, which means governmental MMT program is cost-effective according to the World Health Organization (WHO) criteria.Conclusion: MMT centers are cost-effective in preventing HIV infection and the access to this program should be facilitated for IDU.

Keywords:

Cost-benefit analysis , Methadone , maintenance , Therapeutics , HIV