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Risk Factors for COVID-19-Related Mortality among Hospitalized Patients in Southeastern Iran: A Case-Control Study

Publish Year: 1403
Type: Journal paper
Language: English
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JR_JABS-14-2_008

Index date: 18 August 2024

Risk Factors for COVID-19-Related Mortality among Hospitalized Patients in Southeastern Iran: A Case-Control Study abstract

Background & Objectives: The COVID-19 pandemic has had a devastating global impact, with millions of cases and varying severity of illness. Southeastern Iran has been particularly hard hit, with a high number of patients requiring hospitalization. This study aimed to identify risk factors associated with mortality from COVID-19 among hospitalized patients in this region. Materials & Methods: A case-control study compared hospitalized COVID-19 patients who succumbed to the disease (confirmed by death certificates and positive PCR tests) with those who recovered, from February 27, 2020, to June 30, 2021. Researchers analyzed data using t-tests and chi-square tests to identify significant factors associated with mortality (p < 0.05). Variables significant at a less stringent level (p < 0.2) were then included in a backward logistic regression model to explore independent predictors of mortality. Results: This retrospective study examined data from 473 patients, of whom 158 were in the case group and 315 were in the control group. Among the case group, 80.4% were elderly, compared to 41% in the control group. A significantly higher proportion of patients in the case group (12.7%) experienced critical symptoms leading to ICU hospitalization, compared to the control group (7.3%). Multivariable regression analysis identified several factors significantly associated with increased mortality risk. These included ICU hospitalization (OR=5.27, CI: 3.09-8.98), advanced age (OR=4.06, CI: 2.43-6.80), hypertension (OR=4.44, CI: 1.52-12.93), cardiovascular diseases (OR=2.56, CI: 1.1-5.98), and critical symptoms (OR=2.74, CI: 1.92-8.04).  Diabetes, pregnancy, nationality, and gender did not statistically increase mortality risk (p-value ≥ 0.05). Conclusion: Advanced age, severe symptoms requiring ICU care, hypertension, and cardiovascular diseases are all critical mortality risk factors in hospitalized COVID-19 patients.

Risk Factors for COVID-19-Related Mortality among Hospitalized Patients in Southeastern Iran: A Case-Control Study Keywords:

Risk Factors for COVID-19-Related Mortality among Hospitalized Patients in Southeastern Iran: A Case-Control Study authors

حکمت اله خوب فکر

Center of Health Vice-Chancellor of Iranshahr, University of Medical Sciences and Health Services, Iranshahr, Iran

مطهره عبداللهی

Iranshahr Health Services, Iranshahr University of Medical Sciences, Iranshahr, Iran

حامد امیری

Iranshahr University of Medical Sciences and Health Services, Iranshahr, Iran

صادق امیری

Iranshahr University of Medical Sciences and Health Services, Iranshahr, Iran

صالح بابازاده

Tulane University School of Public Health and Tropical Medicine,Stamford, New Orleans, LA, USA

وحید رحمانیان

Department of Public Health, Torbat Jam Faculty of Medical Sciences, Torbat Jam, Iran

محمد جوکار

Faculty of Veterinary Medicine, Karaj Branch, Islamic Azad University, Karaj, Iran

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