Aptamer-Based Approaches in Oncology

Publish Year: 1403
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_PMJ-9-34_002

تاریخ نمایه سازی: 6 شهریور 1403

Abstract:

Cancer is a significant global cause of mortality, and enhancing therapy is essential to save lives and minimise adverse consequences. Aptamers, composed of DNA or RNA, have the potential for cancer treatment by precise targeting of certain molecules. Aptamers, unlike conventional therapies such as chemotherapy, have the specific objective of delivering medications directly to cancer cells, while reducing injury to healthy cells. This paper examines the process of aptamer development and utilisation in cancer treatment, with a specific emphasis on their capacity to enhance therapy and surmount drug resistance. Additionally, it explores the obstacles and potential advancements in using aptamers to transform cancer therapy.

Authors

Behnoush Khashii

Department of pathobiology, faculty of veterinary science, Bu Ali Sina university, Hamedan, Iran

Parisa Haghpour

Department of Biotechnology, Alzahra Universit, Tehran, Iran