An Effectual Eco-Friendly Protocol for the Construction of 4,6-Diarylpyrimidin-2(1H)-Ones
Publish place: Asian Journal of Green Chmistry، Vol: 8، Issue: 5
Publish Year: 1403
Type: Journal paper
Language: English
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Document National Code:
JR_AJGC-8-5_002
Index date: 14 September 2024
An Effectual Eco-Friendly Protocol for the Construction of 4,6-Diarylpyrimidin-2(1H)-Ones abstract
An effectual eco-friendly protocol for the construction of 4,6-diarylpyrimidin-2(1H)-ones has been described through a solvent-free one-pot multi-component reaction. The condensation of urea, aryl aldehydes, and acetophenones in the Me3SiCl presence produced 4,6-diarylpyrimidin-2(1H)-ones in high yields and relatively short times. In the reported protocols, a catalyst has been used beside Me3SiCl. However, in our protocol, there was no need to utilize a catalyst.
An Effectual Eco-Friendly Protocol for the Construction of 4,6-Diarylpyrimidin-2(1H)-Ones Keywords:
An Effectual Eco-Friendly Protocol for the Construction of 4,6-Diarylpyrimidin-2(1H)-Ones authors
Abdolkarim Zare
Department of Chemistry, Faculty of Nano and Bio Science and Technology, Persian Gulf University, Bushehr ۷۵۱۶۹, Iran
Roghayyeh Khanivar
Department of Chemistry, Payame Noor University, PO Box ۱۹۳۹۵-۳۶۹۷ Tehran, Iran
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