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A study on the gelation time and rheological behavior of injectable hydrogelsbased on carboxymethyl chitosan

Publish place: 16th International Seminar on Polymer Science and Technology (ISPST 2024)
Publish Year: 1403
Type: Conference paper
Language: English
View: 45

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Link to this Paper:
https://civilica.com/doc/2106153

Document National Code:

ISPST16_043

Index date: 30 October 2024

A study on the gelation time and rheological behavior of injectable hydrogelsbased on carboxymethyl chitosan abstract

Carboxymethyl chitosan (CMCS) exhibits biocompatibility, biodegradability, and more bioactivitycompared to chitosan. In this study, hydrogels with three various weight ratios of CMC to oxidizedalginate (1:1, 3:4, and 1:2) were fabricated through Schiff base reactions. The hydrogels werecharacterized in terms of gelation time and rheological behavior. The results demonstrated thatamong the three samples, hydrogel with CMC: alginate oxide ratio of 3:4 revealed the suitablegelation time (10 min). The rheometric mechanical spectroscopy showed that the sample withoptimum gelation time has G’=(10000,100000) and G”=(1000,10000).

A study on the gelation time and rheological behavior of injectable hydrogelsbased on carboxymethyl chitosan Keywords:

Carboxymethyl chitosan , Alginate oxide , Rheological behavior , Gelation time

A study on the gelation time and rheological behavior of injectable hydrogelsbased on carboxymethyl chitosan authors

D Balu

Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran

M Pezeshki-Modaress

Burn Research Center, Iran University of Medical Sciences, Tehran, Iran

N Najmoddin

Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran