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Investigation of the Effects of Genetic V ariants in Human Lung Cancer

Publish place: 4 th international conference of biology and laboratory sciences
Publish Year: 1403
Type: Conference paper
Language: English
View: 27

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Link to this Paper:
https://civilica.com/doc/2201809

Document National Code:

ZISTCONF04_048

Index date: 15 March 2025

Investigation of the Effects of Genetic V ariants in Human Lung Cancer abstract

This article examines the impact of genetic and epigenetic variants on the progression of lung cancer. The resultsshow that genetic mutations such as EGFR, KRAS, and ALK, as well as epigenetic changes like DNAmethylation and histone modifications, contribute to the progression of this disease. Additionally, alterations inDNA repair genes lead to genetic instability and resistance to treatment. Genetic markers such as EGFR andFGFR4 play a crucial role in early detection and targeted therapy. Future research should focus on analyzing thecomplex interactions between these factors to provide better strategies for the prevention and treatment of lungcancer.

Investigation of the Effects of Genetic V ariants in Human Lung Cancer Keywords:

Lung cancer , Genetic variant , Mutation

Investigation of the Effects of Genetic V ariants in Human Lung Cancer authors

Fatemeh Gorzin Mataei

Department of Cellular and Molecular Biology, Comprehensive Health Research Center, Islamic AzadUniversity,Branchbabol,Babol,Iran

Sepideh Mokabberi

Department of Cellular & Molecular Biology , Comprehensive Health Research Center ,Islamic Azad University , Babol Branch ,Babol , Iran ,