Effect of Applicator Changes on Light Propagation and Heat Generation in Biological Tissue During Laser Irradiation in LITT
Publish place: 19th Iranian conference on Biomedical Engineering
Publish Year: 1391
Type: Conference paper
Language: English
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Document National Code:
ICBME19_040
Index date: 29 January 2014
Effect of Applicator Changes on Light Propagation and Heat Generation in Biological Tissue During Laser Irradiation in LITT abstract
Laser Interstitial Thermotherapy (LITT) is a surgical method for treatment of cancer in biological tissues such as liver, brain, prostate and neck. Mathematical modeling of the process in laser-tissue interactions during laser irradiation is essential for optimal treatment planning. In this study, we have analyzed the effect of applicator changes in light propagation and heat generation in biological tissue during LITT. For this purpose a three dimensional model was developed to study applicator changes effects. Monte Carlo Method with variable step size and implicit capture technique was used for simulation of light propagation in tissue. Finite Element Method (FEM) was used for solving Pennes and Arrhenius equations for distribution of temperature and damage in tissue, respectively. The results showed that decreasing the applicator size and its diameter cause higher temperature and damage volume and applicator position in tissue effects the temperature distribution and damage in tissue.
Effect of Applicator Changes on Light Propagation and Heat Generation in Biological Tissue During Laser Irradiation in LITT Keywords:
Effect of Applicator Changes on Light Propagation and Heat Generation in Biological Tissue During Laser Irradiation in LITT authors
Mohammad Ehsan Salavati
M.S. Degree in biomedical engineering, Faculty of Electrical and Computer Engineering, Tarbiat Modares University, Tehran, Iran
Mohammad Hossein Miran Baygi
Mechanical Engineering Department Sharif University of Technology Tehran, Iran.