Mannich-type reactions in a colloidal solution formed by piperidine-۴-carboxylic acid (PPCA) functionalized Fe۳O۴ nanoparticles (Fe۳O۴-PPCA) as the efficient, green and reusable nanocatalyst under solvent free

Piperidine-۴-carboxylic acid (PPCA) functionalized Fe۳O۴ nanoparticles (Fe۳O۴-PPCA) efficiently catalyzed the one-pot, three-component Mannich reaction of ketones with aromatic aldehydes and different anilines in solvent free at a room temperature and afforded the corresponding B-amino carbonyl compounds in good to excellent yields.

Keywords:

Mannich-type reactions , Fe۳O۴-PPCA , B-amino carbonyl compounds , Reusable nanocatalyst