Endobronchial Metastasis of Pheochromocytoma 25 Years after Primary Tumor
Publish place: IRANIAN JOURNAL of PATHOLOGY، Vol: 8، Issue: 2
Publish Year: 1392
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJP-8-2_007
تاریخ نمایه سازی: 5 آبان 1393
Abstract:
There are few reported cases of endobronchial metastasis of pheochromocytoma in pathology literature. We present here a 56-year old woman who underwent left lower lobectomy of lung, following pneumonia with unresolved chest radiographs. Computed tomography showed a lobulatedsoft tissue mass, measuring, 38×27 mm, at the perivascular space of anterior mediastinum. Theresected specimen, showed lobulated tumor arranged in nesting pattern within arcuate vascularnetwork. Immunohistochemistry showed intense positive staining of epitheloid cell (chief cells) for chromogranin and synaptophysin which were negative for cytokeratin. Sustentacular cells were strongly positive for S-100. Although very rare, physicians should keep in mind the possibility of endobronchial metastasis in patients with a history of pheochromocytoma
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Authors
Maryam Kadivar
Dept. of Pathology, Tehran University of Medical Sciences, Tehran, Iran
Pegah Babaheidarian
Dept. of Pathology, Tehran University of Medical Sciences, Tehran, Iran
Ali Zare Mirzae
Dept. of Pathology, Tehran University of Medical Sciences, Tehran, Iran
Mohammadreza Fakhraie
Surgery Ward, Atieh Hospital, Tehran, Iran