A new approach to develop a vaccine against capripox infection insheep and goats using a new strain of sheep pox virus in Iran

This report describes the preparation of a safe and immunogenic single vaccine against capripox disease in sheep and goats using two differenttypes of cells (primary lamb kidney and vero, a bovine turbinate cell line). This used the 0240 pox strain isolated from sheep during an outbreak. Theprepared vaccine was administered subcutaneously and induced complete protection against an experimental sheep and goat pox challenge virus. Forthe final evaluation, the efficacy of the prepared vaccine was used in a field trial under the supervision of veterinary clinicians. This vaccine was provedto be more efficacious than the routine vaccines that are currently produced

Keywords:

Single vaccine , potency , immunogenicity , control , cell culture