SYNTHESIS AND CHARACTERIZATION OF A NEW ZINC(II) COMPLEX CONTAINING DITHIOCARBAMATE LIGAND AS POTENTIAL ANTICANCER AGENT

Novel dithiocarbamate ligand derived from 5-amino-1,3,4-thiadiazole-2-thiol was synthesized. The structure of this ligand was determined on the basis of elemental analysis and spectroscopic techniques. Synthesized dithiocarbamato ligand coordinates to Zn(II) center as bidentate with two sulfur atoms and characterized by elemental analyses, molar conductance, IR, electronic spectra and 1H NMR techniques. This complex is formulated as [Zn(bpy)L]Cl (where bpy = 2,2′-bipyridine and L = 5-dithiocarbamato-1,3,4-thiadiazole-2-thiol).

Keywords:

Dithiocarbamate , 5-amino-1 , 3 , 4-thiadiazole-2-thiol , Zn complex , anticancer agent