IN VIVO EVALUATION OF Bacillus subtilis SPORES THAT ISOLATED FROM soil AS ANIMAL PROBIOTICS

Abstrac Probiotics based on Bacillus strains have been increasingly proposed for prophylactic and therapeutic uses against several gastro-intestinal diseases. One of the important mechanisms of probiotics is the stimulating the immune system. A number of studies in human and animal models have shown that oral administration of spores stimulates the immune system. As a result Spores are not only intestinal harmless passengers but also can be used as food . One feature of B. subtilis spores following oral administration of them is the expanding primary lymphoid tissue associated with gastrointestinal

Keywords:

Bacillus subtilis , probiotics , immunity , toxicity , spore