3D structure analysis of VhhP2 Protein in Vibrio harveyi
Publish place: چهارمین کنفرانس بین المللی علوم و مهندسی
Publish Year: 1395
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ICESCON04_326
تاریخ نمایه سازی: 25 آذر 1395
Abstract:
Vibrio harveyi is one of the significant aquatic pathogens founded predominately in marinehabitats. The gram-negative bacterium can cause infection in a broad range of marine vertebratesand invertebrates, involving fish, shrimp, lobster, and mollusk. Until now, the traditional formsof vaccines against V. harveyi have been produced including killed whole bacterial cells (mostly)and extracellular products (in part). In addition to these vaccines, currently a number of proteinbased(in fact recombinant subunit) vaccines have been manufactures and are shown to beeffective against some V. harveyi starins. The gene of vhhP2 belonged a pathogenic V. harveyistrain isolated from diseased fish has been identified and discovered that vhhP2 is widelydistributed in V. harveyi strains of various geographical locations and sources.The present studywas designed to in silico resolving the major obstacles in the control or in prevention of Vibrioharveyi infections. We exploited bioinformatic tools to better understanding and characterizingthe vhhP2 3Dstructure and select appropriate regions as effective B cell epitops
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Authors
Navid farahmandian
Departeman of biology, Science and Art University, Yazd, Iran
Fateme Sefid
Department of Biology, Shahed University ,Tehran-Qom Express Way
Ehsan Zareian Jahromi
Department of Biology, Kharazmi University, Tehran, Iran
Sara khaleghizadeh
Department of Biology, Payame Nur University, Taft, Iran
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