Cytotoxicity of Carbon Nanotube/Poly(citric acid) Hybrid Nanomaterials

Carbon nanotubes have potential applications as carriers for delivery of drugs, RNA, DNA, peptides and other biological active molecules into the cells because of the ability to crosscell membranes [1-2]. Despite the widely demonstrated potentials of CNTs in nanomedicine, research indicates thesematerials can potentially cause adverse effects on environment and specially health systems [3]. Hence toxicity profile of CNTs is important in biological systems. High hydrophobicity of CNTs causes aggregations and poor solubility in biological systems and therefore heterogeneous interactions with cell components