A Novel Procedure for the Synthesis of Bisarylmethylidene Derivatives of Thiopyran-4-one

An efficient condensation of various aldehydes with thiopyran-4-one is developed in one pot using catalytic quantities of CrCl3.7H2O and SDS in the presence of H2O/pyrrolidine at room temperature. The procedure leads to high yield preparation of bisarylmethylidenes of thiopyran-4-one in relatively short times. Spontaneous precipitation occurs at the end of the process. This leads to easy separation of the products via a simple filtration

Keywords:

Bisarylmethylidenes , aldol condensation , aqueous conditions , organocatalysis , thiopyran