Electrochemical determination of acetaminophen by carbon paste electrodemodified with Nickel-Cobalt salen complexes encapsulated in nano zeolite NaX

Acetaminophen (AC) is a combination of drugs, which are commonly used to treat pain andfever. The liquid chromatography [1] and spectrophotometry [2] analytical techniques have beendeveloped for AC quantification. But, these methods are often expensive and usually need topretreatment or toxicity solvents [3]. AC is an electro-active compound; thereforeelectrochemical technique for the determination of AC drew a lot of attention in the last fewyears due to its simplicity, low cost, high sensitivity and selectivity [3,4]. In this study, a type ofcarbon paste electrode using Ni-Co salen complexes encapsulated in nanozeolite NaX wasprepared and was used for electro-catalytic oxidation of AC in biological samples.

Keywords:

acetaminophen , cyclic voltammetry , salen complex , nano zeolite