validated and Novel Chemiluminescence method for Rapid Determination of Clopidogrel
Publish Year: 1397
Type: Conference paper
Language: English
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Document National Code:
CBGCONF05_126
Index date: 23 April 2019
validated and Novel Chemiluminescence method for Rapid Determination of Clopidogrel abstract
In this article, chemiluminescence (CL) has been used to determine clopidogrel. The method is based on the measurement of the CL intensity in the reaction between Ru(phen)3 2+ and acidic cerium (IV) enhanced by catalytic effect of clopidogrel. The CL intensities was linear over the concentration ranges of 2.0×10-8 to 8.0×10-6 mol L-1. The detection limit (±3) for clopidogrel calculated 1.2×10-8 mol L-1(5.03 ng mL-1 ). The relative standard deviation for 1.0×10-7 mol L-1 clopidogrel was 6.2%. This method successfully applied for the determination of clopidogrel in pharmaceutical formulations. Sampling rate was about 30 samples h-1.
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validated and Novel Chemiluminescence method for Rapid Determination of Clopidogrel authors
Mozhdeh Barati
Department of Chemistry, Golestan University, Gorgan, Iran
Ali Mokhtari
Department of Chemistry, Golestan University, Gorgan, Iran
Massoud karimi
Department of Chemistry, Golestan University, Gorgan, Iran