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Title

An Investigation of Clinical Symptoms and Treatment of Organophosphate Poisoning among Patients Referred to Razi Hospital during 2006 – 2012

Year: 1395
COI: JR_PJMT-5-4_002
Language: EnglishView: 135
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Authors

Azin samimi - Toxicology Research Center, Department of Pharmacology and Toxicology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Ali Hassan Rahmani - Department of Clinical Toxicology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Rojin Ababaf - Medical School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Leila zeidooni - Toxicology Research Center, Department of Pharmacology and Toxicology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Abstract:

Background: Organophosphates are pesticides that are used widely in agriculture and industry. Because of the ease of access and abundant use of these pesticides, many cases of intentional and accidental poisoning of these compounds are reported. The aim of this comprehensive study was to evaluate the symptoms and treatment of patients referred to Razi hospital as the main center for poisoning in the South west of Iran. Methods: In this study, patients with Organophosphate poisoning referred to Razi hospital during the years 2006 to 2012 was included. The information collected from their records includes reference data, demographic data, clinical manifestations and treatment options. Results: Of all 173 cases, 46.2% were male. The average age of cases was 24.31 years and most of them were from rural areas. 86% of patients had deliberately consumed a toxic substance. The first clinical symptoms of more than half of the patients were nausea and vomiting. 72.8% of patients needed antidote; a combination of atropine and pralidoxim was administered in 70% of cases. 16.2% required intubation and 80% admitted to ICU. In 52% of cases a specified pesticide was found and 4% of the cases deceased. Conclusion: Organophosphate poisoning in most cases occurred deliberately as a suicidal attempt. It was more common in rural areas.  Need for admission to intensive care unit was more common in cases under the age of twenty. Treatment of patients with both antidote atropine and pralidoxime was a very suitable therapeutic model.

Keywords:

antidote, Iran, Organophosphate, Suicide

Paper COI Code

This Paper COI Code is JR_PJMT-5-4_002. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/890632/

How to Cite to This Paper:

If you want to refer to this Paper in your research work, you can simply use the following phrase in the resources section:
samimi, Azin and Rahmani, Ali Hassan and Ababaf, Rojin and zeidooni, Leila,1395,An Investigation of Clinical Symptoms and Treatment of Organophosphate Poisoning among Patients Referred to Razi Hospital during 2006 – 2012,https://civilica.com/doc/890632

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  • Tsai JR, Sheu CC, Cheng MH, Hung JY, Wang CS, ...
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  • van Heel W, Hachimi-Idrissi S. Accidental Organophosphate Insecticide Intoxication in ...
  • Peter JV, Sudarsan TI, Moran JL. Clinical Features of Organophosphate ...
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  • Yurumez Y, Durukan P, Yavuz Y, Ikizceli I, Avsarogullari L, ...
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  • Robenshtok E, Luria S, Tashma Z, Hourvitz A. Adverse Reaction ...
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