Current Concepts in Scaffolding for Bone Tissue Engineering
Publish place: The Archives of Bone and Joint Surgery، Vol: 6، Issue: 2
Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
View: 389
This Paper With 10 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_TABO-6-2_002
تاریخ نمایه سازی: 18 تیر 1398
Abstract:
Bone disorders are of significant worry due to their increased prevalence in the median age. Scaffold-based bonetissue engineering holds great promise for the future of osseous defects therapies. Porous composite materials andfunctional coatings for metallic implants have been introduced in next generation of orthopedic medicine for tissueengineering. While osteoconductive materials such as hydroxyapatite and tricalcium phosphate ceramics as wellas some biodegradable polymers are suggested, much interest has recently focused on the use of osteoinductivematerials like demineralized bone matrix or bone derivatives. However, physiochemical modifications in terms ofporosity, mechanical strength, cell adhesion, biocompatibility, cell proliferation, mineralization and osteogenicdifferentiation are required. This paper reviews studies on bone tissue engineering from the biomaterial point of viewin scaffolding.
Keywords:
Authors
Toktam Ghassemi
Department of Chemical Engineering, Ferdowsi University of Mashhad, Mashhad, Iran
Azadeh Shahroodi
Targeted Drug Delivery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Mohammad H. Ebrahimzadeh
Orthopedic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Alireza Mousavian
Orthopedic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran