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Title

A comparative study about toxicity of CdSe quantum dots on reproductive system development of mice and controlling this toxicity by ZnS coverage

Year: 1394
COI: JR_NAMJ-2-4_003
Language: EnglishView: 265
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Authors

Akram Valipoor - Department of Physiology, Faculty of Basic Sciences, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
Gholamreza Amiri - Department of Physics, Falavarjan Branch, Islamic Azad University, Isfahan, Iran
Kazem Parivar - Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
Mehrdad Modaresi - Department of Physiology, Islamic Azad University, Khorasgan Branch, Isfahan, Iran

Abstract:

Objective(s):  Medicinal benefits of quantum dots have been proved in recent years but there is little known about their toxicity especially in vivo toxicity. In order to use quantum dots in medical applications, studies ontheir in vivo toxicity is important.  Materials and Methods:CdSe:ZnS quantum dots were injected in 10, 20, and 40 mg/kg doses to male mice10 days later, mice were sacrificed and five micron slides were prepared structural and optical properties of quantum dots were evaluated using XRD.   Results:    Histological studies of testis tissue showed high toxic effect of CdSe:ZnS  in 40 mg/kg group. Histological studies of epididymis did not show any effect of quantum dots in terms of morphology and tube structure. Mean concentration of LH and testosterone and testis weight showed considerable changes in mice injected with 40 mg/kg dose of CdSe:ZnS compared to control group. However, FSH and body weight did not show any difference with control group.  Conclusion:   Although it has been reported that CdSe is highly protected from the environment by its shell, but  this study showed high toxicity for CdSe:ZnS when it is used in vivo which could be suggested that shell could contribute to increased toxicity of quantum dots. Considering lack of any previous study on this subject, our study could potentially be used as an basis for further extensive studies investigating the effects of quantum dots toxicity on development of male sexual system.

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Paper COI Code

This Paper COI Code is JR_NAMJ-2-4_003. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/893488/

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Valipoor, Akram and Amiri, Gholamreza and Parivar, Kazem and Modaresi, Mehrdad,1394,A comparative study about toxicity of CdSe quantum dots on reproductive system development of mice and controlling this toxicity by ZnS coverage,https://civilica.com/doc/893488

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Scientometrics

The specifications of the publisher center of this Paper are as follows:
Type of center: Azad University
Paper count: 3,713
In the scientometrics section of CIVILICA, you can see the scientific ranking of the Iranian academic and research centers based on the statistics of indexed articles.

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