A novel label-free cocaine assay based on aptamer-wrapped single-walled carbon nanotubes

Publish Year: 1393
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_NAMJ-1-2_006

تاریخ نمایه سازی: 18 تیر 1398

Abstract:

Objective(s): This paper describes a selective and sensitive biosensor based on the dissolution and aggregation of aptamer wrapped single-walled carbon nanotubes. We report on the direct detection of aptamer–cocaine interactions, namely between a DNA aptamer and cocaine molecules based on near-infrared absorption at λ807. Materials and Methods: First a DNA aptamer recognizing cocaine was non-covalently immobilized on the surface of single walled carbon nanotubes and consequently dissolution of SWNTs was occurred. Vis-NIR absorption (A807nm) of dispersed, soluble aptamer-SWNTs hybrid, before and after incubation with cocaine was measured using a CECIL9000 spectrophotometer. Results: This carbon nanotube setup enabled the reliable monitoring of the interaction of cocaine with its cognate aptamer by aggregation of SWNTs in the presence of cocaine. Disscusion: This assay system provides a mean for the label-free, concentration-dependent, and selective detection of cocaine with an observed detection limit of 49.5 nM.

Authors

Sahar Taghavi

Pharmaceutical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | Department of Pharmaceutical Biotechnology, Mashhad University of Medical Sciences, Mashhad, Iran

Sara Ayatollahi

Pharmaceutical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | Department of Pharmaceutical Biotechnology, Mashhad University of Medical Sciences, Mashhad, Iran

Mona Alibolandi

Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Parirokh Lavaee

Department of Chemistry, Ferdowsi University of Mashhad, Mashhad, Iran

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  • Cekan P, Jonsson Eض, Sigurdsson ST. Folding of the cocaine ...
  • Liu J, Lu Y. Non-base pairing DNA provides a new ...
  • Liu J, Lu Y. Rational design of turn-on allosteric DNAzyme ...
  • Zhang J, Wang L, Pan D, Song S, Boey FYC, ...
  • Stojanovic MN, Landry DW. Aptamer-based colorimetric probe for cocaine. J ...
  • Baker BR, Lai RY, Wood MS, Doctor EH, Heeger AJ, ...
  • Stojanovic MN, Parada P, de, Landry DW. Aptamer-based folding fluorescent ...
  • Stojanovic MN, de Parada P, Landry DW. Fluorescent sensors based ...
  • Shlyahovsky B, Di L, Weizmann Y, Nowarski R, Kotler M, ...
  • Liu J, Lee JH, Lu Y. Quantum dot encoding of ...
  • Jhaveri SD, Kirby R, Conrad R, Maglott EJ, Bowser M, ...
  • Liss M, Petersen B, Wolfe H, Prohaska E. An aptamer-based ...
  • Tuerk C, Gold L. Systematic evolution of ligands by exponential ...
  • Nutiu R, Li Y. Structure-switching signaling aptamers. J Am Chem ...
  • Avouris, P. Molecular electronics with carbon nanotubes. Acc Chem Res. ...
  • Bachilo, SM, Strano MS, Kittrell C, Hauge RH, Smalley RE, ...
  • Barone PW, Baik S, Heller DA, Strano MS. Near-infrared optical ...
  • Heller DA, Baik S, Eurell TE, Strano MS. Single-walled carbon ...
  • Wray S, Cope M, Delpy DT, Wyatt JS, Reynolds EOR. ...
  • Chen H, Yu C, Jiang C, Zhang S, Liu B, ...
  • Tasis D, Tagmatarchis N, Bianco A, Prato M: Chemistry of ...
  • Lin Y, Taylor S, Li H, Fernando KAS, Qu L, ...
  • Bahr JL, Tour JM: Covalent chemistry of single-wall carbon nanotubes. ...
  • Banerjee S, Hemraj-Benny T, Wong SS: Covalent surface chemistry of ...
  • Tasis D, Tagmatarchis N, Georgakilas V, Prato M. Soluble carbon ...
  • Sun YP, Fu K, Lin Y, Huang W: Functionalized carbon ...
  • Niyogi S, Hamon MA, Hu H, Zhao B, Bhowmik P, ...
  • Chou SG, Plentz F, Jiang J, Saito R, Nezich D, ...
  • Arnold MS, Guler MO, Hersam MC, Stupp SI: Encapsulation of ...
  • Kam NWS, Jessop TC, Wender PA, Dai H: Nanotube molecular ...
  • Heller DA, Jeng ES, Yeung TK, Martinez BM, Moll AE, ...
  • Chen H, Yu C, Jiang C, Zhang S, Liu B, ...
  • Zuker M. Mfold web server for nucleic acid folding and ...
  • Taghdisi SM, Lavaee P, Ramezani M, Abnous K. Reversible targeting ...
  • Hamula CLA, Guthrie JW, Zhang H, Li XF, Le XC. ...
  • Zhou J, Ellis AV, Kobus H, Voelcker NH. Aptamer sensor ...
  • Cone EJ, Hillsgrove M, Darwin WD. Simultaneous measurement of cocaine, ...
  • Chinn DM, Crouch DJ, Peat MA, Finkle BS, Jennison TA. ...
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