Dental pulp and periodontal regeneration; advanced scaffolds and biomaterials

Although human mouth benefits from remarkable mechanical properties, it is very susceptible to traumatic damages, exposure to microbial attacks, and congenital maladies. Since the human dentition plays a crucial role in mastication, phonation, esthetics and interpersonal relationships, finding promising and more efficient strategies to reestablish its functionality in the event of disruption has been important. Dating back to antiquity, conventional dentistry has been offering evacuation, restoration, and replacement of the diseased dental tissue. However, due to the limited ability and short lifespan of traditional restorative solutions, scientists have taken advantage of current advancements in medicine to create better solutions for the oral health field and have coined it regenerative dentistry. This new field takes advantage of the recent innovations in stem cell research, cellular and molecular biology, tissue engineering, and materials science etc. This review focuses on an overview of the recent advancements in regenerative dentistry and advanced scaffolds and biomaterials used in dental pulp and periodontal regeneration. A search was conducted in electronic databases such as Medline, Science Direct and PubMed from 2010 to 2018 with theseRegenerative medicine therapy for dental and craniofacial tissues is a rapidly developing field, and the advances of this field has the potential to improve the health of dental and craniofacial patients in the near future.

Keywords:

Dental tissue engineering , Regenerative dentistry , Scaffolds , Biomaterials