The effect of natural adjuvants (G2, G2F) on lung inflammation of sensitized guinea pigs
Publish place: Avicenna Journal of Phytomedicine، Vol: 3، Issue: 4
Publish Year: 1392
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_AJP-3-4_009
تاریخ نمایه سازی: 1 مهر 1398
Abstract:
Objective: The effects of natural adjuvants were examined on total and differential WBC counts in lung lavage of sensitized guinea pigs. Materials and Methods: In three sensitized groups of guinea pigs including: untreated sensitized animals (S), sensitized animals treated with adjuvant G2 (S+G2) and G2F (S+G2F) as well as non-sensitized group (C) (n=6 for each group), total and differential WBC counts of lung lavage were examined. Sensitization of animals was achieved by injection and inhalation of ovalbumin (OA). Results: The results showed increased total WBC, eosinophil, neutrophil, and basophil counts, and decreased lymphocytes in lung lavage of sensitized animals compared with the control group (pConclusion: These results indicate important preventive effects of two natural adjuvants, especially G2, on lung inflammation of sensitized guinea pigs.
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Authors
Ali Neamati
Department of Biology, Faculty of Science, Islamic Azad University, Mashhad Branch, I. R. Iran
Mohammad Hossein Boskabady
Applied Physiology Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I. R. Iran
Saleh Mohaghegh Hazrati
School of Public Health, Tehran University of Medical Sciences and Researches on Industrial Biotechnology, Tehran, I. R. Iran
Mohammad Reza Khakzad
Islamic Azad University, Mashhad Branch, and Zakaria Research Center, Mashhad, I. R. Iran
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