Brucellosis seroprevalence in the normal and high-risk individuals in Iran: A systematic review and meta-analysis

Objective: Brucellosis is an zeonotic disease and it is a health and economic problem in many parts of theworld, including Iran. The disease is endemic in Iran and the reported cases increased, however, diseaseoutbreaks are not clear. This review aimed to determine the prevalence of brucellosis in normal and high-riskpopulation in Iran.Methods: This systematic review and meta-analysis was performed in article about Brucellosis in Iran.Systematic search was conducted in the databases, include: Pubmed, Scopus, SID (as a local database) untilAugust 2015. Finally we have 454 article after deleting duplicating material by Endnote software. Dataextraction form contains author, publication year, sample size, laboratory test, study population in normalperson and high risk person and seroprevalence. Finally, Data were analyzed by STATA 11.1 and randomeffect.Results: Finally, we enrolled 11 studies and 7688 person in high risk group and 13858 person in normal groupwere studied. The seroprevalence of brucellosis in normal population was 0.12 (CI95%: 0.08 - 0.17). Theseroprevalence of brucellosis in High-risk population was 13.07(CI95%: 12.3 - 13.7).Conclusion: The prevalence of brucellosis in high-risk occupations was high in comparison with normalpopulation and it seems that control of livestock diseases should be considered more.

Keywords:

Seroprevalence , Brucellosis , High-risk population