Case Report: Successful Pregnancy Following Recurrent Implantation Failure with Clinical Laboratory Strategy

In a treatment cycle of in vitro fertilization (IVF), 15% of the oocytes are immature and present in germinal vesicle (GV) phase. Rarely happens, more than 50% of the oocytes of one patient are immature per cycle. It is an enormous challenge to select the kind of treatment for infertility in these patients. The patient was a 35-year-old woman who had primary infertility for 10 years. She had undergone 6-time unsuccessful infertility treatment cycles of IVF during the treatment. In these cycles, more than 50% of the oocytes were immature and in GV phase. In this matter, we developed a coordinated clinical-embryology laboratory therapeutic protocol for the patient by studying the patient’s medical records of unsuccessful cycles. The development of a special and coordinated clinical-embryology laboratory protocol was efficient, as compared with the commonly used independent clinical and laboratory protocols, to achieve the best outcomes in such patients

Keywords:

Assisted Reproductive Techniques , Infertility , In Vitro Fertilization