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Plants of the Genus Heracleum as a Source of Coumarin and Furanocoumarin

Publish place: Journal of Chemical Reviews، Vol: 1، Issue: 2
Publish Year: 1398
Type: Journal paper
Language: English
View: 483

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Link to this Paper:
https://civilica.com/doc/964621

Document National Code:

JR_JCHM-1-2_001

Index date: 8 December 2019

Plants of the Genus Heracleum as a Source of Coumarin and Furanocoumarin abstract

Heracleum is one of the greatest genera of the Umbelliferae family that has more than 120 species. This genus is represented by 109 species in Asia. Common names for the genus or its species include hogweed and cow parsnip. This paper discusses the phytochemistry, ethnopharmacological use and pharmaceutics of Heracleum species. Many kinds of metabolites have been isolated and identified, that furanocoumarins are among the significant ones. Modern pharmacological studies demonstrated that Heracleum and its active compounds have extensive biological activity, particularly in anticonvulsant, anti-inflammatory, antifungal, anticancer, anti-psoriatric, anti-vitiligo and antioxidant activities. In clinical test, Heracleum has successfully been utilized to treat psoriasis, vitiligo, carminative, stomachs, pain killer and anticonvulsant.

Plants of the Genus Heracleum as a Source of Coumarin and Furanocoumarin Keywords:

Heracleum , Furanocoumarins , Coumarins , Anticovulsant , anti-inflammatory

Plants of the Genus Heracleum as a Source of Coumarin and Furanocoumarin authors

Zahra Hosseinzadeh

Department of Chemistry, University of Zanjan, Zanjan, Iran

Ali Ramazani

Department of Chemistry, University of Zanjan, Zanjan, Iran

Nima Razzaghi-Asl

Department of Medicinal Chemistry, School of Pharmacy, Ardabil University of Medical Sciences, Ardabil, Iran

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