Published in: 3rd national congress on clinical case reports
COI code: CCRMED03_365
Paper Language: English
How to Download This Paper
For Downloading the Fulltext of CIVILICA papers please visit the orginal Persian Section of website.
Authors Malignant melanoma of the male urethra: a case reportShiva Shakeri - Medical Student, Student Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Nafiseh Ansarinejad - MD, Department of Medical Oncology and Hematology, Iran University of Medical Sciences, Tehran, Iran
Sahar Emami - Medical Student, Student Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Pegah Babaheidarian - Assistant Professor of Pathology, Iran University of Medical Sciences, Tehran, Iran
Abstract:Malignant melanoma of the penis is a rare malignancy, and accounts for less than 2% of all primary penile malignant lesions. Most cases occur in 6th and 7th decades of life. Most frequently, the lesion is located on the glans(55%), followed by foreskin(28%), penile shaft(9%) and urethral meatus(8%). 5-year survival is 31%.A 52-year-old man presented to hospital with history of a lesion extruded from urethral meatus. He did not mention any complaints of pain or lower urinary tract symptoms. On physical examination, there were no remarkable findings. No palpable inguinal lymphadenopathy was found.During cystoscopy, a grayish-brown mass was detected in the urethra. The lesion was resected and specimens were sent to pathology. IHC and histopathologic findings were in favor of malignant melanoma. Spiral chest and abdominopelvic CT-scan and whole body bone scan indicated no evidence of metastasis. The patient underwent partial penectomy and bilateral inguinal lymphadenectomy therewith. Subsequent pathology examination confirmed malignant melanoma with tumor size of 2.8cm in greatest diameter, and maximum tumor (Breslow) thickness of 8mm. Tumor was classified as stage2B according to AJCC TNM staging system(T4aN0M0).Ultra-Sound imaging of kidneys, ureters, bladder, penis and testes was performed and no remarkable findings were detected. The patient underwent total body PET-CT scan and abdominopelvic MRI with and without contrast; A hypodense hyper-metabolic lesion was indicated in favor of perineal abscess. Serology, biochemistry and hematologic investigations were all normal. After surgery, interferon-therapy was started for the patient as 5,000,000 units of alpha-interferon every other day for one year. Penile melanomas are usually diagnosed late; Many might have already invaded into deep anatomical structures and inguinal lymph-nodes at the time of diagnosis. Therefore, partial or total penectomy with inguinal lymph-node dissection is the treatment of choice. Early diagnosis and surgical treatment affect clinical prognosis.
Keywords:Melanoma, Urethra, Penis, Penectomy
COI code: CCRMED03_365
how to cite to this paper:If you want to refer to this article in your research, you can easily use the following in the resources and references section:
Shakeri, Shiva; Nafiseh Ansarinejad; Sahar Emami & Pegah Babaheidarian, 2019, Malignant melanoma of the male urethra: a case report, 3rd national congress on clinical case reports, كرج, دانشگاه علوم پزشكي و خدمات بهداشتي و درماني البرز, https://www.civilica.com/Paper-CCRMED03-CCRMED03_365.htmlInside the text, wherever referred to or an achievement of this article is mentioned, after mentioning the article, inside the parental, the following specifications are written.
First Time: (Shakeri, Shiva; Nafiseh Ansarinejad; Sahar Emami & Pegah Babaheidarian, 2019)
Second and more: (Shakeri; Ansarinejad; Emami & Babaheidarian, 2019)
For a complete overview of how to citation please review the following CIVILICA Guide (Citation)
The University/Research Center Information:
Type: Medical University
Paper No.: 3020
in University Ranking and Scientometrics the Iranian universities and research centers are evaluated based on scientific papers.
Research Info Management
Export Citation info of this paper to research management softwares
New Related Papers
- Orf virus infection in human ecthyma contagiosum : a case report in the north estern of Iran
- A report of three cases of cutaneous anthrax in Iran, a public health issue of continuing concern in Iran
- Simultaneous salmonella septic arthritis and naïve-valve endocarditis
- Pregnancy in a Rudimentary Horn with a Live 19-Weeks Fetus: a Case Report
- Two Reportable Rare Syndromes in Pediatric field: Griscelli Syndrome Type II along with Hemophagocytic lymphohistiocytosis
The Above articles are recently indexed in the related subjects
Iran Scientific Advertisment Netword
Share this paper
WHAT IS COI?
COI is a national code dedicated to all Iranian Conference and Journal Papers. the COI of each paper can be verified online.