Adenoid Cystic Carcinoma of Breast: A Rare Case Report
Publish place: Archives of Breast Cancer، Vol: 5، Issue: 1
Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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JR_ARCHB-5-1_008
تاریخ نمایه سازی: 24 خرداد 1400
Abstract:
Background: Adenoid cystic carcinoma (AdCC) of the breast is a rare type ofinvasive breast cancer, accounting for less than ۱% of all breast cancer cases. It isusually a low-grade tumor that rarely metastasizes to the axillary lymph nodes anddistant organs. AdCC of the breast is mostly negative for estrogen receptor,progesterone receptor, and HER۲-neu. However, despite being triple-negative, ithas favorable outcome, and patients with AdCC of the breast generally have a goodto excellent long-term survival. Case presentation: Here we report a case of a ۵۱-year-old female presentingwith left breast mastalgia who was finally diagnosed with AdCC of the left breast.The patient underwent breast-conserving surgery and axillary staging followed byadjuvant chemoradiation. Conclusion: Because of the rarity of AdCC of the breast, it has been difficult toconduct prospective trials to determine the best treatment option. Different types oftherapy, including BCS and mastectomy with or without axillary staging with orwithout adjuvant chemoradiation have been reported, all with overall good toexcellent long-term results. Prospective controlled trials will help in determiningthe best treatment.
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Authors
Negar Mashoori
Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran
Sanaz Zand
Kaviani Breast Disease Institute (KBDI), Tehran, Iran
Shahram Movafaghi
Department of Pathology, Laleh Hospital, Tehran, Iran
Farid Azmoudeh-Ardalan
Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran
Ahmad Kaviani
Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran- Kaviani Breast Disease Institute (KBDI), Tehran, Iran