Clinical and Para-clinical Features of Brucellosis With and Without Spondylodiscitis
Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JCMI-8-2_002
تاریخ نمایه سازی: 30 مرداد 1401
Abstract:
Background: Brucellosis is a common zoonotic disease with protean clinical manifestations. Osteoarticularinvolvement is the most common complication of the disease. This study aimed to compare the clinical andpara-clinical manifestations of brucellosis among the patients with and without spondylodiscitis.Methods: In this comparative and cross-sectional study, ۱۳۵ patients having brucellosis with and withoutspondylodiscitis and admitted to Sina hospital in Hamadan, Iran from March ۲۰۰۹ to March ۲۰۱۴ wereincluded. Clinical and para-clinical data of the patients were obtained from their medical records in the hospitalbased on a designed checklist.Results: Thirty-five patients having brucellar spondylodiscitis (BS) with the mean age of ۵۵.۶۰ ± ۱۴.۳۱ years,and ۱۰۰ patients having brucellosis without BS with the mean age of ۴۳.۲۷ ± ۱۸.۳۵ years were examined.A significant difference was found between the mean age of the patients with spondylodiscitis and that ofthose without spondylodiscitis (P < ۰.۰۰۱). All patients with spondylodiscitis complained of back pain andvertebral tenderness, while ۶۰% of the patients without BS suffered from back pain but experienced no vertebraltenderness (P = ۰.۰۰۳). The most common vertebral involvement in spinal MRI of the patients with BS was L۴-L۵(۴۵.۷%). Patients with spondylodiscitis had more increased ESR and CRP than those without spondylodiscitis(P < ۰.۰۰۱).Conclusion: It is recommended that Brucellar spondylodiscitis be considered in the differential diagnosis of thepatients with prolonged fever, back pain, and vertebrae tenderness in the endemic areas.
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Authors
Fariba Keramat
Brucellosis Research Center, Department of Infectious Diseases, Hamadan University of Medical Sciences, Hamadan, Iran
Seyyed Hamid Hashemi
Brucellosis Research Center, Department of Infectious Diseases, Hamadan University of Medical Sciences, Hamadan, Iran
Farzaneh Esna-Ashari
Department of Community of Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Kaveh Kaseb
General Practitioner, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran