Preparation of bioactive polymer-based composite by different techniques and application in tissue engineering: A review

Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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JR_JRCC-3-8_002

تاریخ نمایه سازی: 30 مرداد 1401

Abstract:

Tissue engineering (TE) employs biological, chemical, and engineering methods to regenerate and restore injuredor lost living tissues by applying biologically activated biomaterials, cells, and molecules. The fast and convenientrestoration of tissue is a great challenge, emphasizing the need to imitate tissue structure and its physicochemical,biological, and mechanical behavior to give back the desired functionality of damaged tissue. Depending onthe particular tissue, numerous requirements have to be fulfilled with the help of material and scaffold designthat provides a base for cell adhesion and proliferation. As a result, countless biodegradable and bioresorbablematerials have been extensively examined. Composite systems combine the benefits of bioactive ceramics andpolymers, which seem to be good alternatives for bone tissue engineering. This article intends to introduce bioactivepolymer, tissue engineering methods, the kinds of biomaterials applied in scaffold invention, and the differentapproaches to producing the bioactive polymer-based composites with various structures such as porous, membrane,and ۳D structure. Biomaterials and invention techniques could crucially influence the consequences of thescaffold's design architectures, cell proliferation, and mechanical behavior. Moreover, an excellent scaffold assistscell generation and the provision of cell nutrients in the human body with their particular material characteristics.

Authors

Alireza Alipour

Mechanical Engineering Department, Universiti Teknologi Petronas, Seri Iskandar ۳۲۶۱۰, Perak, Malaysia

Somaye Mohammadi

Hot Deformation and Thermomechanical Processing Laboratory of High-Performance Engineering Materials, School of Metallurgy and Materials Engineering,College of Engineering, University of Tehran, Tehran, Iran

Pouran Pourhakkak

Department of Chemistry, Payame Noor University, P.O. Box ۱۹۳۹۵-۱۶۹۷ Tehran, Iran

Lukas Gritsch

Laboratoire de Physique de Clermont, CNRS/IN۲P۳, Université Clermont Auvergne, ۴ Avenue Blaise Pascal, ۶۳۱۷۸ Aubière (Clermont-Ferrand),France

Alireza Alipour

Medical Biotechnology Research Center, Ashkezar Branch, Islamic Azad University, Yazd, Iran

Somaye Mohammadi

Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, ۸۷۳۱۷-۵۱۱۶۷, I.R. Iran