Biocides Susceptibility of Clinically Isolated Escherichia coli in Presence and Without Organic Material
Publish place: Iranian Journal of Medical Microbiology، Vol: 16، Issue: 5
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IJMM-16-5_010
تاریخ نمایه سازی: 16 مهر 1401
Abstract:
Background and Aim: Hospital-acquired infections are considered a major health concern worldwide because of the increasing morbidity and mortality rate. Hence, selecting the most efficient disinfectants in a clinic is crucial. This study evaluated the antibacterial efficacy of seven mostly used disinfectants against clinically isolated Escherichia coli.
Materials and Methods: For this purpose, minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) of Aniosyme DD۱ ۰.۵%, Steranios ۲%, Aniospray ۲۹ and Surfanios ۰.۵% at Hazrat Valiasr hospital and PROSEPT® Floor ۰.۷۵%, PROSEPT® Instru ۰.۰۵% and PROSEPT® Med used at Ayatollah Mousavi hospital were determined both in the presence and absence of bovine serum albumin (BSA) using microbroth dilution assay.
Results: The results indicate that PROSEPT® Med had the lowest MIC and MBC values, followed by Aniospray ۲۹ and PROSEPT® Instro, and the presence of BSA reduced antibacterial activities of disinfectants.
Conclusion: The disinfectants applied at Ayatollah Mousavi hospital generally had higher antibacterial activities. Due to the importance of nosocomial pathogens at healthcare centers, selecting the most potent, fast-acting, and efficient disinfectants to prevent hospital-acquired infections is essential.
Keywords:
Disinfectants , Escherichia coli , Hospital-acquired infections , Minimum bactericidal concentrations , Minimum inhibitory concentrations , ضد عفونی کننده ها , اشریشیا کلی , عفونت های بیمارستانی , حداقل غلظت باکتری کش , حداقل غلظت های بازدارنده
Authors
Hamidreza Lotfi
Zanjan pharmaceutical biotechnology research center, Zanjan University of Medical Sciences, Zanjan, Iran
Tina Khalilzadeh
Department of Medicine, Faculty of Medicine, Laval University, Quebec, Canada
Maryam Damchi
Zanjan pharmaceutical biotechnology research center, Zanjan University of Medical Sciences, Zanjan, Iran
Maryam Hassan
Zanjan pharmaceutical biotechnology research center, Zanjan University of Medical Sciences, Zanjan, Iran
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